New cerebellar ataxia gene identified in dogs

Researchers have identified the genetic cause of early-onset progressive cerebellar degeneration the Finnish Hound dog breed. The study revealed a new disease mechanism in cerebellar degeneration. A mutation was identified in the SEL1L gene, which has no previous link to inherited cerebellar ataxias. At the same time, SEL1L represents a novel candidate gene in human early-onset degenerative ataxias.

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