Lymphoma drug shrinks dog tumors, could lead to human treatment

There are many kinds of cancers of the immune system, but one, activated B-cell diffuse large B-cell lymphoma, is particularly common and pernicious. Researchers have now shown that dogs that develop this disease spontaneously share the same aberrant activation of a critical intracellular pathway with humans. They also found that a drug designed to disrupt this pathway helps kill tumor cells in the dogs’ lymph nodes.

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